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2025 PDS&T - Bioprocess Modeling Intern (Mixed Wet/Dry)

AbbVie

AbbVie

Worcester, MA, USA
Posted on Dec 5, 2024

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Bioprocess Modeling Intern (Mixed Wet/Dry) Overview

Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie Interns.

As an intern on the Cell Culture and Process Development team within the Product Development Science and Technology group, you will have an incredible opportunity to make a direct impact on process development optimization strategy while developing a mixed wet/dry lab skillset. The goal of this experience (past developing a working model of optimized batch mixing) is to become fully embedded in both sides of the computational workflow by not only transitioning mathematical concepts to fully usable web applications, but also benchmarking the output of those models by running the predictions alongside traditional design settings in 3L bioreactors. This multi-faceted experience is then expected to translate into a well-developed ability to cross-functionally communicate.

Key Responsibilities Include:

  • Intern will be mentored as needed on how to analyze, design, test, and productionize a python based optimization model that ingests spectral, process, and QC data.
  • Intern will first manually, then automatically, curate and structure mixed datasets, learning the rationale and mathematical basis in the process.
  • Intern will train and test data on historical DoE batch mixing results, before using that model to predict a subset of optimized mixture combinations.
  • Intern will conduct traditional DoE in 3L Bioreactors to validate predicted optimal lot/batch mixtures and confirm the validity of this approach.
  • Intern will analyze results of the benchmark testing to assess the effect of mixing 2 to n batches, the accuracy of the predicted results, and the ability of the model to reduce experimental burden while maintaining accuracy.

Qualifications

Minimum Qualifications

  • Currently enrolled in university, pursuing a Bachelor’s in Biochemistry, Chemical Engineering, Computational Biology, Systems Biology, Computer Science or other related field
  • Must be enrolled in university for at least one semester following the internship
  • Expected graduation date between December 2025 – June 2026
  • Wet lab experience

Preferred Qualifications

  • Exposure to cell culture
  • Proficiency in Python

Additional Information

Benefits and Amenities

  • Competitive pay
  • Relocation support for eligible students
  • Select wellness benefits and paid holiday / sick time

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html