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Senior Manager, Warehouse and Logistics (Holly Springs)

Genentech

Genentech

Operations
Holly Springs, NC, USA
USD 117k-217k / year
Posted on Feb 19, 2026

The Position

Welcome to Holly Springs, North Carolina— home to Roche/Genentech's largest-ever investment: a $2B greenfield start-up where next-generation technology, high-performing teams and Operational Excellence converge to create the global standard for high-volume, highly-efficient Drug Product manufacturing.

The facility's core is defined by Innovation - leveraging advanced automation, robotics, digital tools, real-time data analytics, and simple, streamlined processes to produce the highest quality medicines. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes. This is a fast-paced, entrepreneurial environment with a high-level of accountability, with planned launch in 2028.

Are you a problem-solver and change-agent who thrives in a Team environment, eager to tackle the most complex manufacturing challenges? If so, this is a once-in-a-lifetime opportunity to launch a state-of-the-art facility from the ground-up and shape the culture of our organization for the next generation.

Join us in Holly Springs, where you won't just build a plant—you will build the future of medicine.

The Opportunity

Pre-Startup:

As the Warehouse & Logistics Senior Manager, you are accountable for the comprehensive and timely ramp-up of all warehouse-related activities, ensuring full compliance with cGMP requirements throughout the design, qualification, and validation lifecycle. You will identify timeline risks or bottlenecks for the project timeline and take appropriate actions. You will work closely with all key project stakeholders to achieve ambitious goals in terms of on-time, on-cost, and on-scope delivery.

The warehouse will be highly automated and this role will act as the business lead for implementing SAP/eWM and other IT systems for inventory management. This includes defining specifications and processes requirements, testing, local procedure development, and ensuring the warehouse team is trained and ready for startup.

Post-Startup:

Following the successful go-live and validation, you will transition into the Warehouse & Logistics leadership role. As the owner of all Warehouse systems and assets, you are accountable for the safe, accurate, and efficient preparation, maintenance, calibration, functionality, and reliability of all respective areas, equipment, and processes. You will build and effectively execute the agenda for warehouse operations to ensure reliable delivery for commercial products. You will build and maintain strong partnerships with other Manufacturing units, Quality, MSAT, Facility, Engineering & SHE, ITOT, and other functional areas to assure site goals are achieved.

Initially, you will perform a mix of remote and onsite work (first at the General Planner’s office, later at construction site/plant). Travel of up to 30% of the time is expected during this phase. You will transition to full time on-site work at Holly Springs, NC in mid-2026.

  • You will develop and execute the long-term vision and strategy for the warehouse, aligning with the company's overall business objectives.

  • You will oversee all day-to-day warehouse activities, including receiving, put-away, picking, packing, and shipping, ensuring optimal efficiency and accuracy.

  • You will manage the performance and maintenance of advanced warehouse automation systems, including robotics, conveyors, and automated storage and retrieval systems (AS/RS). Collaborate with engineering and IT teams to troubleshoot issues and drive continuous improvement.

  • You will ensure strict adherence to all regulatory guidelines (e.g., FDA, EMA, DEA) and company quality standards. Maintain meticulous records and prepare for audits.

  • You will hire, lead, mentor, and develop a high-performing team. Foster a culture of safety, quality, and continuous improvement.

  • You will establish and monitor key performance indicators (KPIs) to track operational efficiency, quality, and cost. Use data to identify trends and drive decision-making.

  • You will lead site Warehouse activities for SAP deployment fit-to-template, design, test, SOP development, go-live, and hypercare

Who You Are

  • You hold a Bachelor's degree in Supply Chain Management, Logistics, Business Administration, or a related field with at least 5 years in a leadership role within the pharmaceutical, biotech, or healthcare industries.

  • You have proven experience working with and managing automated warehouse systems.

  • You have in-depth knowledge of pharmaceutical regulations, including FDA, EMA, and DEA requirements.

  • You have strong analytical and problem-solving skills, with the ability to use data to drive decisions.

  • You have excellent communication and interpersonal skills, with the ability to lead and motivate a diverse team.

  • You have experience with Warehouse Management Systems (WMS) and other supply chain technologies.

  • You have a demonstrated ability to manage complex projects and drive change in a large organization.

Preferred:

  • You have post Graduate-level course work, including management training (e.g., MBA)

  • You have APICS (CPIM) supply chain certification

The expected salary range for this position based on the primary location for this position of Holly Springs is $117,000 - $217,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Link to Benefits

Relocation benefits are provided

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.