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Senior /Principal Business Manager, gRED ESPC

Genentech

Genentech

Sales & Business Development
South San Francisco, CA, USA
USD 132,900-290,700 / year
Posted on Apr 7, 2026

The Position

As a Business Manager for the gRED Governance system (DB/BB, ESPC, RRC) you will play a pivotal role in enabling high-quality decision making across gRED. This individual will report to the Head of gRED Governance Office in the PSM organization.

You will serve as a partner to the ESPC Chairs and functional leadership to facilitate scientific, technical, and business decision reviews and execution. The business manager will have a primary role within ESPC and will act in coordination with their business manager colleagues to cover each other and coordinate across DB/BB and RRC.

This position requires a blend of strategic acumen, operational excellence, and systems thinking to connect people, processes, and insights across the organization.

The Opportunity:

As a valuable member on the PSM team you will be:

Governance

  • Ensuring seamless decision-making processes and coordination across other governance committees

  • Partnering with governance chairs, members, and portfolio teams to design optimal review and endorsement pathways that enable timely, high-quality decisions.

  • Developing engagement models with governance leads to ensure consistency, transparency, and effective advice-seeking.

  • Creating and continuously improve resources, tools, and frameworks that enhance governance clarity, traceability, and impact.

  • Championing the evolution of the community as an interconnected system with shared accountability, continuous learning, and a unified approach to governance.

  • Leading or contributing to cross-enterprise change initiatives, embedding learning loops and continuous improvement practices into governance operations.

Operations and Leadership

  • Accountable for ESPC operations: agendas, briefing preparation to decision documentation and communication.

  • Partner with Asset Teams and project leaders to ensure materials and discussions are strategic, concise, and decision-ready.

  • Brief Chairs and participants on critical topics, ensuring inclusive, well-informed, and action-oriented dialogue.

  • Capture discussions and decisions with accurate meeting minutes, ensuring outcomes are clearly communicated, documented, and acted upon in a timely manner.

  • Drive strong cross-functional collaboration across various governance committees and portfolio teams.

  • Collaborate closely with Business Managers across gRED and Roche to enable integrated and coordinated governance.

  • Serve as a central hub for ESPC-related inquiries, communications, and stakeholder engagement.

  • Partner with the gRED Governance Office team to continuously improve and enhance gRED governance processes.

Who You Are:

  • Bachelor’s degree in Science, Business, Engineering, or related field required; advanced degree (MBA, PhD, PharmD, MS, MPH, MD) preferred; 5+ years of experience (Senior) 10+ years of experience (Principal)

  • Broad understanding of drug development across stages; commercial or therapeutic area knowledge is an asset.

  • Demonstrated experience in governance, portfolio management, business operations, or enterprise process design.

  • Extremely high attention to detail: meeting minutes fully reflect discussion and action items

  • Communication Mastery: Strong written, verbal, and presentation skills; able to distill complexity into actionable insights.

  • Facilitation Excellence: Exceptional ability to manage high-stakes discussions with diverse scientific and business leaders and able to partner with senior leaders and Chairs

  • Operational Rigor: Strong organizational and project management discipline with a bias for clarity, follow-through, and accountability.

  • Collaborative Mindset: Skilled in fostering alignment across boundaries with humility, curiosity, and trust.

Preferred Qualifications and Mindset

  • Curious Learner: Seeks continuous growth and intentionally develops self and others.

  • Connector: Actively shares learnings and leverages knowledge across networks.

  • Enabler: Encourages distributed accountability and empowers decision-making.

  • Strategic Communicator: Balances transparency with discretion, ensuring clarity of intent and message.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is 132,900.00 - 246,700 (Senior Business Manager) and 156,500- $290,700 (Principal Business Manager). Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.