The Position

Finance Manager – Month End Close / Systems SME

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love

The Opportunity:

The eCoE is focusing on three areas delivering a high-level of financial expertise, relevant insights, and an entrepreneurial mindset that enables stakeholders to make business decisions. The eCoE is a talent engine for Finance through capability building and network building. There are three focus areas within eCoE:

● Financial Backbone

● Digital Innovation

● Analytics and Insights

This role ensures the accuracy, integrity, and audit-readiness of financial reporting across the organization. The candidate will oversee Month-End Close (MEC) activities by coordinating global and local teams, aligning reporting processes, and delivering consistent variance analysis to ensure a controlled, predictable close.

In addition, the role will drive improvements in financial systems, governance, and submission workflows, transitioning processes toward a more automated and structured framework. Overall, the position plays a key role in safeguarding financial data integrity and ensuring reliable, enterprise-level reporting.

Key Roles & Responsibilities:

• Ensure a single source of truth by maintaining 100% accuracy and reconciliation between local sub-ledgers and global reporting systems.

• Own the end-to-end US financial data load process, ensuring accurate, timely, and seamless integration into global platforms.

• Maintain complete and traceable audit trails for all executive-level reporting, supporting transparency and compliance.

• Lead and coordinate Month-End Close (MEC) activities, aligning cross-functional teams to meet global deadlines.

• Drive variance analysis and synthesis, connecting local accounting results to global financial performance insights.

• Oversee financial systems architecture and data flows, ensuring consistency from operational systems through executive reporting tools.

• Partner with key stakeholders, including eCOE, local finance teams, Controllers, and global partners, to ensure alignment and execution.

• Act as a governance lead with high visibility, managing competing priorities while safeguarding the integrity of financial reporting.

Who You Are:

• Bachelor’s degree required; Master’s degree or MBA preferred.

• Demonstrated ability to streamline close and reporting processes, improving consistency, efficiency, and control.

• Strong analytical skills with the ability to leverage data insights to identify, validate, and explain financial variances.

• Experience applying advanced tools and technologies (including AI-enabled solutions) to support reconciliation and anomaly detection.

• Deep technical finance expertise with a strong focus on data integrity, reporting accuracy, and governance across regional inputs.

• Solid understanding of financial systems and data flows, with the ability to identify structural issues and ensure reliable end-to-end reporting.

Location: South San Francisco, CA

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of San Francisco, CA is $96,600 - $179,400. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.