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Senior Principal Electrical Engineer

Medtronic

Medtronic

Other Engineering
northridge, los angeles, ca, usa
USD 162,400-243,600 / year + Equity
Posted on Jan 9, 2026
We anticipate the application window for this opening will close on - 15 Jan 2026


At Medtronic you can begin a life-long career of exploration and innovation, while helping champion healthcare access and equity for all. You’ll lead with purpose, breaking down barriers to innovation in a more connected, compassionate world.

A Day in the Life

Medtronic Diabetes is seeking a highly experienced Senior Principal Electrical Engineer with specialized expertise in electrochemical biosensing to lead the development of next-generation medical devices. This role requires deep technical knowledge in biosensor design, electrochemical systems, and medical device regulations to drive innovation in diagnostic and therapeutic applications.

As a Senior Principal Electrical Engineer, you will play a critical leadership role in the design, development, and optimization of cutting-edge electrochemical glucose sensor technology for diabetes management. You will provide technical expertise, drive innovation, and guide cross-functional teams to deliver safe, effective, and reliable medical devices that improve patient outcomes. Candidates must be willing to work in a fast-paced, multi-tasking, team environment.

Join a passionate team dedicated to transforming diabetes care through innovative sensor technology. You’ll have the opportunity to make a meaningful impact on patients’ lives and work with some of the brightest minds in the medical device industry.


This position is an exciting opportunity to work with Medtronic's Diabetes business. Medtronic has announced its intention to separate the Diabetes division to promote future growth and innovation within the business and reallocate investments and resources across Medtronic, subject to applicable information and consultation requirements. This separation provides our team with a bold opportunity to unleash our potential, enabling us to operate with greater speed and agility. As a separate entity, we anticipate leveraging

Responsibilities may include the following and other duties may be assigned. ​

Technical Leadership:

  • Lead the electrical design and development of advanced electrochemical glucose sensor systems, including circuitry, embedded systems, and signal processing algorithms.

  • Define and execute verification and validation strategies for sensor electronics, ensuring compliance with relevant medical device standards (ISO 13485, IEC 60601, etc.).

  • Drive innovation through the evaluation and adoption of new materials, sensor architectures, and low-power electronics.

  • Oversee design documentation, risk analysis, and failure mode analysis (FMEA) for sensor-related components.

  • Interface with external partners, suppliers, and research organizations to advance sensor technology.

  • Present technical findings and project updates to executive leadership and cross-functional stakeholders.

Design & Development:

  • Architect electrical systems for continuous glucose monitors or other diagnostic platforms

  • Develop signal conditioning circuits, analog front ends, and data acquisition systems for biosensor applications

  • Design low-noise, high-precision potentiostat circuits and amperometric measurement systems

  • Develop algorithms for signal processing, noise reduction, and biomarker detection

  • Create electrical interfaces between biosensors and embedded systems

  • Optimize sensor performance parameters including sensitivity, selectivity, and stability

  • Drive innovation in sensor miniaturization, power optimization, and wireless connectivity

Technical Oversight:

  • Collaborate with chemistry, mechanical, software, systems, and manufacturing teams to integrate sensor technology into commercial diabetes devices.

  • Mentor and guide junior engineers and project teams in design best practices, troubleshooting, and root cause analysis.

  • Review and approve electrical designs, test protocols, and validation procedures

  • Lead design reviews and risk analysis activities

Regulatory & Quality:

  • Ensure designs comply with FDA regulations (21 CFR Part 820), IEC 60601, and ISO 13485

  • Support regulatory submissions including 510(k) and PMA applications

  • Implement design controls and verification/validation protocols per medical device standards

  • Partner with regulatory and quality teams to support submissions, audits, and compliance activities.

Required Knowledge and Experience:

Requires a Bachelor's degree and minimum of 10 years of relevant experience OR Master's degree with a minimum of 8 years relevant experience OR PhD with 6 years relevant experience.

Nice to Have:

  • MS or PhD Degree in Electrical Engineering or Applied Physics

  • 5+ years of hands-on experience with electrochemical biosensing systems

  • Deep understanding of electrochemical principles (cyclic voltammetry, impedance spectroscopy, potentiometry)

  • Proven experience designing potentiostat circuits and electrochemical instrumentation

  • Proficiency in analog circuit design, mixed-signal systems, and low-power electronics

  • Experience with biosensor fabrication techniques and electrode materials

  • Knowledge of biocompatibility requirements and sensor packaging for biological environments

  • Strong background in signal processing and data analysis for biosensor applications

  • Experience with wireless communication protocols (Bluetooth, NFC) for medical devices

  • Proficiency in circuit simulation tools (SPICE, Cadence) and PCB design (Altium )

  • Deep knowledge of PCBA design and manufacturing processes

  • Understanding of medical device regulations and quality systems

  • Excellent leadership, communication, problem-solving and analytical skills

  • Experience with design for manufacturability, reliability, and testability in a regulated environment.

  • MS or PhD in Electrical Engineering, Biomedical Engineering or related field

  • Previous experience with continuous glucose monitoring or other implantable sensors

  • Knowledge of machine learning applications in biosensor data analysis

  • Experience with ISO 14971 risk management processes

  • Publication record in peer-reviewed journals related to biosensing

  • Experience leading cross-functional teams in regulated environments

  • Hands-on experience with microfabrication, MEMS, or biosensor integration.

  • Knowledge of diabetes care products and user needs.

  • Proficiency with simulation and modeling tools (e.g., SPICE, MATLAB).

  • Track record of patents, publications, or contributions to industry standards.

  • Knowledge of manufacturing test equipment design

  • Experience working with vendors and contract manufacturers for PCB fabrication and assembly

Physical Job Requirements

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.

The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.

Benefits & Compensation

Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.

Salary ranges for U.S (excl. PR) locations (USD):$162,400.00 - $243,600.00

This position is eligible for a short-term incentive called the Medtronic Incentive Plan (MIP).

The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).

The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance, Health Savings Account, Healthcare Flexible Spending Account, Life insurance, Long-term disability leave, Dependent daycare spending account, Tuition assistance/reimbursement, and Simple Steps (global well-being program).

The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match, Short-term disability, Paid time off, Paid holidays, Employee Stock Purchase Plan, Employee Assistance Program, Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).

Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.

Further details are available at the link below:

Medtronic benefits and compensation plans

About Medtronic

We lead global healthcare technology and boldly attack the most challenging health problems facing humanity by searching out and finding solutions.
Our Mission — to alleviate pain, restore health, and extend life — unites a global team of 95,000+ passionate people.
We are engineers at heart— putting ambitious ideas to work to generate real solutions for real people. From the R&D lab, to the factory floor, to the conference room, every one of us experiments, creates, builds, improves and solves. We have the talent, diverse perspectives, and guts to engineer the extraordinary.

Learn more about our business, mission, and our commitment to diversity here.

It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.

If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.