Find Your Dream Job Today

Our mission is to help high-achieving LGBTQ+ undergraduates reach their full potential.

Principal Scientist; Vaccines Analytical Research & Development



West Point, PA, USA
Posted on Thursday, April 11, 2024

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology, we collaborate to discover the next medical breakthrough.

We are seeking Principal Scientist to join our Vaccine Analytical Research and Development team located in West Point, PA. In this role, an individual will work closely with the group Director to define group strategy and lead a team of scientists in solving complex analytical problems to facilitate vaccine process and formulation development. The individual should have in-depth knowledge in protein chemistry, structural biology, and biochemistry with specific experience relating to a variety of vaccine platforms (live virus vaccines, virus like particles, recombinant protein vaccines, mRNA vaccines). We are looking for a team player with strong leadership skills and ability and passion for mentoring and working along with others in a laboratory setting. This position will involve leading laboratory development and execution of methods to drive understanding of vaccines product and process. In addition, partnering across functions and divisions to strategically apply that understanding to deliver the best science in the process and product will be a key responsibility. Applicants must have effective organizational and multi-tasking skills, have demonstrated excellent scientific leadership, and have superior written and oral communications skills. A track record of delivering impactful solutions to complex analytical problems, and evidence of strong cross-functional collaboration is expected. Experience leading small groups of technical personnel, leading projects, and defining group or departmental strategy will aid in distinguishing candidates. An established reputation for scientific excellence supported by publications and external presentations is expected.

Primary Responsibilities:

  • Lead and supervise a team of scientists applying analytical methods to support vaccine process development, formulation development, vaccine investigations, vaccine characterization, method qualifications and transfers.

  • Apply strong analytical capabilities and experience for analysis of large molecules, vaccines, and analytical method development and troubleshooting.

  • Lead in authoring and reviewing scientific documents including development reports, analytical method protocols, qualification protocols, and electronic notebooks.

  • Work and collaborate effectively in a multidisciplinary team environment and provide technical input to enable team decisions.

Education Minimum Requirement:

  • Ph.D. in analytical chemistry/biochemistry or related field with a minimum of 8 years of experience in the pharmaceutical industry, M.S. in analytical chemistry/biochemistry or related field with a minimum of 12 years of experience in the pharmaceutical industry, or B.S. in analytical chemistry/biochemistry or related field with a minimum of 16 years of experience in the pharmaceutical industry.

Required Experience and Skills:

  • Demonstrated ability to develop talent through good mentoring skills.

  • Demonstrated ability for taking initiative, creativity and innovation in problem solving.

  • Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment.

  • Experience with analysis of large molecules, vaccines virus like particles.

  • Experience with analytical method development.

  • Ability to troubleshoot technical issues related to analytical methods.

  • Excellent verbal and written communication skills.

  • Capable of multi-tasking and managing multiple projects.

  • Motivated to learn new skills, willingness to take on new challenges, and scientific curiosity.

Preferred Experience and Skills:

  • Established scientific reputation supported by publications and external presentations.

  • Familiar with ICH guideline of analytical procedure validation and transfer.

  • Experience with assay robustness evaluation, method validation or qualification.

  • Experience with method transfer.

  • Solid computer skills, experienced with automated laboratory instrumentation, and independent analytical problem-solving capabilities.




In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:



VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Not Applicable


Valid Driving License:

Hazardous Material(s):

Job Posting End Date:


*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:06/14/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R287765