Job Description

The department of Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) is seeking a dynamic leader for our growing Translational PK/PD organization. The Translational PK/PD Director is responsible for driving application of our modeling and simulation capabilities to enable earlier and more confident decision making around PK/PD, modality selection and dose prediction across all therapeutic areas for small molecule, peptide and protein therapeutics. Directors are responsible for achieving results via others on program deliverables while also being responsible for talent development and performance management of their staff, regularly interacting with multi-disciplinary discovery teams and partners from other functions within our company.

The Translational PK/PD Director role will be responsible for providing strategic leadership and talent management for the group through:

• Leading a team of scientists including people management, scientific and operational oversight, under the direction of the Associate Vice President of Data Automation and Translation (DAT)

• Leveraging drug discovery, translational and disease area expertise to independently provide day-to-day scientific oversight to individual contributors to identify and optimize drug candidates

• Improving the diversity of our teams, ensuring equity of opportunity and an inclusive workplace

• Identifying resource needs and contributes to resource allocation internally and through management of business operations including travel and outsourcing budgets

• Working with DAT leadership to contribute to the development and execution of departmental priorities and ensure broad alignment of individual priorities/performance of team with the DAT and larger PDMB vision and mission

• Providing functional representation on committees, task forces or initiatives

In addition to the responsibilities described above, Directors demonstrate outstanding leadership and communication skills collaborating across PDMB and with other functional areas to create a quantitative model-informed approach to impact program strategies and decision making on drug discovery teams through the application of translational PK/PD, mechanistic and PBPK models.

Required:

• PhD or equivalent degree with at least 7 years of drug discovery or development experience or MS/PharmD with at least 10 years of experience

• A record of both internal and external impact in driving model-informed drug discovery and translational PK/PD strategies

• Demonstrated track record in establishing an inclusive and high-performance work environment through building talent, fostering collaboration, driving results and overseeing the work of other scientists

• Experience in performing hands-on translational PK/PD modeling including PBPK and mechanistic PK/PD for small molecules and protein therapeutics

Preferred:

• Expert skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics

• Proficiency in written and verbal communication, interdisciplinary collaboration, and problem scoping and planning.

• Emerging leader in the field of translational PK/PD with a track record of external visibility, through publications, presentations and/or involvement in professional organizations

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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Current Contingent Workers apply HERE

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We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected US salary range:

$200,200.00 - $315,100.00

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic/International

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Required Skills:

Business Intelligence (BI), Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Machine Learning, Software Development, Stakeholder Relationship Management, Waterfall Project Management

Preferred Skills:

Job Posting End Date:

10/7/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:10/07/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R309119