Associate Principal Scientist, Large Molecule High-throughput Experimentation within Data-Rich Experimentation
Merck
Job Description
Position Description:
Large Molecule High-throughput Experimentation Associate Principal Scientist within Data-Rich Experimentation
We are seeking an Associate Principal Scientist to join our Data-Rich Experimentation (DRE) organization, within Process Research & Developing Enabling Technologies (PR&D ET), located in West Point, PA.
Primary Responsibilities:
In this role, the chosen candidate will work with a team of scientists tasked with identifying, developing, and deploying data-rich technologies aimed at improving the manner in which process understanding is gathered. The tools that we develop are as diverse as the team developing them, and in this Associate Principal Scientist role, the chosen candidate will leverage high-throughput experimentation and data science technologies to enable our process research and development efforts across our Company's small molecule, biologics, and vaccines portfolio.
Our Data-Rich Experimentation (DRE) organization is responsible for the invention and application of new data-rich tools to support the scientists across process research and development at our Company. We aspire to embed data-intense technologies into the fabric of our Company’s process development culture. This Associate Principal Scientist role is a scientific position tasked with solving complex process research and development challenges in an interdisciplinary, collaborative environment via invention, development, and application of innovative high-throughput experimentation tools. Ultimately, using cutting-edge automation and data science capabilities, we aim to elucidate a deeper understanding of our processes across diverse medicines and vaccines.
In this Associate Principal Scientist role, the chosen candidate will leverage high-throughput experimentation and data science capabilities to help advance process-focused scientific research.
This includes, but is not limited to,:
delivering high throughput process development (HTPD) solutions to process teams and conducting microscale screening experiments as required to drive large molecule development,
identifying opportunities to utilize HTPD and developing novel HTPD workflows to enhance process understanding,
efficient programming, implementing and maintaining robotic systems with liquid-handling hardware,
leveraging digital tools to enable automated data pipeline such as algorithm-assisted experimental planning and automated data aggregation, analysis and visualization.
In addition to a passion for high-throughput experimentation and data science, the chosen candidate should have excellent interpersonal, communication, and collaboration skills. The chosen candidate should embrace and model our core values of diversity and inclusion, including fostering a supportive culture where all can thrive. The chosen candidate should be able to effectively collaborate in a dynamic, integrated, and multidisciplinary team environment. The chosen candidate should demonstrate a clear ability to perform impactful scientific innovation in a team-oriented manner that builds trusted partnerships across vast stakeholder networks. The chosen candidate should have a demonstrated ability to publish and present research, including an established track record of interaction with the broader academic community. The chosen candidate will join a diverse group of scientific problem solvers who are dedicated to creating the life-changing medicines and vaccines of tomorrow.
Position Qualifications:
Education Minimum Requirement:
A Ph.D. in Engineering, Chemistry, Physics, Biology, Pharmaceutical Sciences, or a closely-related field with at least 3 years of industrial/pharmaceutical or relevant experience
A M.S. in Engineering, Chemistry, Physics, Biology, Pharmaceutical Sciences, or a closely-related field with at least 5 years of industrial/pharmaceutical or relevant experience
A B.S. in in Engineering, Chemistry, Physics, Biology, Pharmaceutical Sciences, or a closely-related field with at least 7 years of industrial/pharmaceutical or relevant experience
Required Experience and Skills:
Relevant working experience in identifying and implementing high-throughput process development (HTPD) solutions for application to large biomolecule process development (e.g. viral vectors, vaccines, therapeutic proteins).
Strong technical background in large biomolecules upstream (e.g. microbial fermentation, mammalian cell & virus culture) or downstream (e.g. harvest, filtration, chromatography, conjugation) unit operations.
Experience in developing and implementing microscale models for large molecule upstream or downstream process unit operations.
Highly-motivated and technology-centric scientist that is passionate about modernizing our Company’s process development practices across biologics, vaccines, and small molecule modalities.
Demonstrated scientific ability through publications and presentations in scientific conferences.
Excellent communication skills, demonstrated creativity, and effective interpersonal skills.
Ability to deliver complex solutions under compressed timelines in a dynamic environment.
Ability to work in a team environment with cross-functional interactions.
Preferred Experience and Skills:
Expertise in implementing data science tools to accelerate high-throughput lab automation capabilities.
Experience in new technology research, including a demonstrated track record of identifying, developing, and deploying data-rich tools and methodologies.
Collaborative research efforts that are praised by the broader scientific community and are exemplary of a multidisciplinary group.
Evidence of cross-functional collaboration in an academic or industrial setting.
Motivated to learn new skills, willingness to take on new challenges, and scientific curiosity.
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Employee Status:
RegularRelocation:
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Travel Requirements:
Flexible Work Arrangements:
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Job Posting End Date:
10/1/2024*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Job Posting End Date:10/01/2024
A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Requisition ID:R310464